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[Policy Forum] Computational Science: Troubling Trends in Scientific Software Use

Science: Current Issue - Thu, 05/16/2013 - 17:11
"Blind trust" is dangerous when choosing software to support research.

Authors: Lucas N. Joppa, Greg McInerny, Richard Harper, Lara Salido, Kenji Takeda, Kenton O'Hara, David Gavaghan, Stephen Emmott
Categories: Science and Nature

[Perspective] Ecology: Immunity and Invasive Success

Science: Current Issue - Thu, 05/16/2013 - 17:11
The Asian harlequin ladybird has successfully invaded ecosystems around the world with the help of a pathogen that it carries. [Also see Report by Vilcinskas et al.]

Author: Stuart E. Reynolds
Categories: Science and Nature

[Perspective] Cell Biology: Insulin Finds Its Niche

Science: Current Issue - Thu, 05/16/2013 - 17:11
Localized insulin signaling allows organ-specific rather than organism-level responses to the environmental conditions.

Authors: Seth W. Cheetham, Andrea H. Brand
Categories: Science and Nature

[Perspective] Materials Science: Quartz on Silicon

Science: Current Issue - Thu, 05/16/2013 - 17:11
The integration of quartz with silicon may provide a route to fabricate advanced piezoelectric devices. [Also see Research Article by Carretero-Genevrier et al.]

Authors: C. Jeffrey Brinker, Paul G. Clem
Categories: Science and Nature

[Perspective] Virology: Our Viral Inheritance

Science: Current Issue - Thu, 05/16/2013 - 17:11
Viruses incorporated into vertebrate genomes may reemerge after long periods of dormancy to play a range of biological roles in their host.

Authors: Robin A. Weiss, Jonathan P. Stoye
Categories: Science and Nature

[Perspective] Applied Physics: Ghost Imaging in Three Dimensions

Science: Current Issue - Thu, 05/16/2013 - 17:11
Single-pixel detectors can be used to reconstruct three-dimensional images after patterned illumination of an object. [Also see Report by Sun et al.]

Authors: Daniele Faccio, Jonathan Leach
Categories: Science and Nature

[Perspective] Materials Science: Complexity from Simplicity

Science: Current Issue - Thu, 05/16/2013 - 17:11
Manipulation of crystal growth conditions results in the controlled formation of complex micrometer-scale shapes. [Also see Research Article by Noorduin et al.]

Author: Elias Vlieg
Categories: Science and Nature

[Perspective] Medicine: (Poly)Combing the Pediatric Cancer Genome for Answers

Science: Current Issue - Thu, 05/16/2013 - 17:11
Misregulation of the pattern and localization of histone modifications may result in cancer development. [Also see Report by Lewis et al.]

Authors: Marc Alard Morgan, Ali Shilatifard
Categories: Science and Nature

[Retrospective] Retrospective: Robert G. Edwards (1925–2013)

Science: Current Issue - Thu, 05/16/2013 - 17:11
The work of a pioneer of in vitro fertilization led to the first "test-tube baby" and changed the field of human reproductive biology.

Authors: Susan J. Fisher, Linda C. Giudice
Categories: Science and Nature

[Research Article] Soft-Chemistry–Based Routes to Epitaxial α-Quartz Thin Films with Tunable Textures

Science: Current Issue - Thu, 05/16/2013 - 17:11
Porous and dense piezoelectric films of α-quartz crystals are epitaxially grown on silicon substrates. [Also see Perspective by Brinker and Clem]

Authors: A. Carretero-Genevrier, M. Gich, L. Picas, J. Gazquez, G. L. Drisko, C. Boissiere, D. Grosso, J. Rodriguez-Carvajal, C. Sanchez
Categories: Science and Nature

[Research Article] Rationally Designed Complex, Hierarchical Microarchitectures

Science: Current Issue - Thu, 05/16/2013 - 17:11
Complex solids are crafted through small changes to the solution conditions in a reaction-diffusion coupled system. [Also see Perspective by Vlieg]

Authors: Wim L. Noorduin, Alison Grinthal, L. Mahadevan, Joanna Aizenberg
Categories: Science and Nature

[Research Article] Dual Molecular Signals Mediate the Bacterial Response to Outer-Membrane Stress

Science: Current Issue - Thu, 05/16/2013 - 17:11
Gram-negative bacteria monitor lipopolysaccharide and outer-membrane protein status to detect and respond to problems.

Authors: Santiago Lima, Monica S. Guo, Rachna Chaba, Carol A. Gross, Robert T. Sauer
Categories: Science and Nature

[Report] Phase Diagram of the Topological Superfluid 3He Confined in a Nanoscale Slab Geometry

Science: Current Issue - Thu, 05/16/2013 - 17:11
Geometrical confinement affects the stability of the superfluid phases of helium-3.

Authors: L. V. Levitin, R. G. Bennett, A. Casey, B. Cowan, J. Saunders, D. Drung, Th. Schurig, J. M. Parpia
Categories: Science and Nature

[Report] 3D Computational Imaging with Single-Pixel Detectors

Science: Current Issue - Thu, 05/16/2013 - 17:11
A computational imaging method is used to reconstruct a three-dimensional scene, without the need for lenses. [Also see Perspective by Faccio and Leach]

Authors: B. Sun, M. P. Edgar, R. Bowman, L. E. Vittert, S. Welsh, A. Bowman, M. J. Padgett
Categories: Science and Nature

[Report] Computationally Assisted Identification of Functional Inorganic Materials

Science: Current Issue - Thu, 05/16/2013 - 17:11
A method using extended building blocks is developed for computationally viable predictions of stable crystal structures.

Authors: Matthew S. Dyer, Christopher Collins, Darren Hodgeman, Philip A. Chater, Antoine Demont, Simon Romani, Ruth Sayers, Michael F. Thomas, John B. Claridge, George R. Darling, Matthew J. Rosseinsky
Categories: Science and Nature

[Report] A Reconciled Estimate of Glacier Contributions to Sea Level Rise: 2003 to 2009

Science: Current Issue - Thu, 05/16/2013 - 17:11
A model is developed to describe the complex dynamics of dry foams across a range of time and length scales.

Authors: Alex S. Gardner, Geir Moholdt, J. Graham Cogley, Bert Wouters, Anthony A. Arendt, John Wahr, Etienne Berthier, Regine Hock, W. Tad Pfeffer, Georg Kaser, Stefan R. M. Ligtenberg, Tobias Bolch, Martin J. Sharp, Jon Ove Hagen, Michiel R. van den Broeke, Frank Paul
Categories: Science and Nature

[Report] Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

Science: Current Issue - Thu, 05/16/2013 - 17:11
Mutations of histones in some cancers result in inhibition of enzymes that lay down epigenetic marks on chromatin. [Also see Perspective by Morgan and Shilatifard]

Authors: Peter W. Lewis, Manuel M. Müller, Matthew S. Koletsky, Francisco Cordero, Shu Lin, Laura A. Banaszynski, Benjamin A. Garcia, Tom W. Muir, Oren J. Becher, C. David Allis
Categories: Science and Nature

[Report] Invasive Harlequin Ladybird Carries Biological Weapons Against Native Competitors

Science: Current Issue - Thu, 05/16/2013 - 17:11
Invasive ladybugs harbor microsporidia that kill nonresistant beetles contributing to the original residents’ decline. [Also see Perspective by Reynolds]

Authors: Andreas Vilcinskas, Kilian Stoecker, Henrike Schmidtberg, Christian R. Röhrich, Heiko Vogel
Categories: Science and Nature

[Report] Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MAL

Science: Current Issue - Thu, 05/16/2013 - 17:11
A dynamic polymeric actin structure inside the nucleus is part of the serum response in mammalian tissue culture cells.

Authors: Christian Baarlink, Haicui Wang, Robert Grosse
Categories: Science and Nature

[Report] Wnt Stabilization of β-Catenin Reveals Principles for Morphogen Receptor-Scaffold Assemblies

Science: Current Issue - Thu, 05/16/2013 - 17:11
The scaffold protein Axin has an active role in modulating signaling through the Wnt pathway.

Authors: Sung-Eun Kim, He Huang, Ming Zhao, Xinjun Zhang, Aili Zhang, Mikhail V. Semonov, Bryan T. MacDonald, Xiaowu Zhang, Jose Garcia Abreu, Leilei Peng, Xi He
Categories: Science and Nature

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